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INFORMATION FOR HEALTHCARE PROFESSIONALS
This information is intended for a healthcare professional audience only. If you are not a healthcare professional, please visit our consumer site.

Introducing Ocutears

Long-lasting relief from dry eye symptoms. Ocutears ionic and cross-linked formulas work to keep eye drops in place, so they are long lasting and may not need to be applied as often.1-6*

Ocutears Your dry eye partner

*compared to alternative eye drops which use a sodium hyaluronate formula which isn’t cross-linked

97% FEEL FRUSTRATED BY THE IMPACT OF SYMPTOMS†

†in a survey of 751 participants

Dry eye disease (DED) can negatively affect quality of life and lock patients into a cycle of frustration.8

Pain and discomfort8
Blurred vision8
Poor sleep quality8
Negative feelings8
Lower concentration8
Gets in the way of leisure8

BREAK THE DED FRUSTRATION CYCLE

  • DED can be a vicious cycle8
  • To break it, restoring the ocular surface and tear film integrity may be important8
  • Eye drops are the principal approach8
  • But frequent eye drop applications are challenging, particularly for those with poor vision or dexterity9
  • How often they need to reapply is considered most important to patients when it comes to using an eye drop (96%‡)10

‡in a survey of 160 people.

What is Dry Eye Disease?

WHAT MAKES OCUTEARS DIFFERENT

Ocutears’ ionic (Cationorm) and cross-linked formulas 0.4% sodium hyaluronate (Alo+ and Hydro+) formulas are long lasting and are designed to stay put on the eye where they are needed.1-6 That means potentially fewer applications*, with relief from just one drop a day.1-6  All our products are preservative free and contact lens friendly.1,2,4

*compared to alternative eye drops which use a sodium hyaluronate formula.

Why choose Ocutears?    How do Ocutears work?

  • Ocutears Hydro+

    Ocutears Hydro+

    Long lasting hydration and relief from sore, stinging, gritty, tired, heavy or watery eyes caused by dry eye.1

    Download instructions for use

    Your customer

    Busy and needs an eye drop that they can rely on and can apply less often.* Mild-moderate DED.1,2,6

    RRP £14.99**

  • Ocutears® Alo+

    Ocutears Alo+

    Relieves symptoms of red, irritated and sensitive eyes for prolonged freshness and long-lasting comfort.2 Also contains cross-linked version of 0.4% sodium hyaluronate.2

    Download instructions for use

    Your customer

    Mainly concerned about redness or general irritation.2 Also for travellers, those with irritation from sun exposure, air conditioning or a dry environment.2 Mild-moderate DED.1,2,6

    RRP £14.99**

  • Cationorm bottle with messaging saying: New packaging coming soon

    Cationorm

    Unique advanced triple-action dry eye science.6 Acts like the body’s natural tears to provide long-lasting relief.6

    Download instructions for use

    Your customer

    Those with regular symptoms that could be exacerbated by the menopause or other conditions.4,11,12,32 Also suitable for those who have undergone eye surgery and want something to help with the discomfort.4,13 Moderate-severe DED.6,13,14

    RRP £14.99**

** Excl. VAT. Based on RRP £14.99. Pricing is at the sole discretion of the retailer. Any reference to pricing is for modelling purposes only.

 

Download the HCP leaflet

THE BENEFITS OF CROSS-LINKED

Ocutears Hydro+ and Alo+ contain sodium hyaluronate (0.4%) at a higher concentration than other artificial tears.1,2,6,15 Sodium hyaluronate hydrates, lubricates and acts as a barrier to prevent irritation16:

  • Most sodium hyaluronate in eye drops is in a linear form16,17
  • Cross-linking involves linking together different chains of sodium hyaluronate with two or more bonds, which:
  • Increases viscoelasticity16,17
  • Works to keep the eye drops in place1,15,18
  • Means they may not need to be reapplied as often (vs alternatives without cross-linked sodium hyaluronate)1,3,15
  • Provided long lasting hydration and DED symptom relief1

THE BENEFITS OF IONIC

  • Clinically proven, Cationorm is a first-of-a-kind artificial tear which uses ionic technology to mimic the body’s natural tears and provide long-lasting relief:4,6,19
  • Cetalkonium chloride (CKC) brings the ionic ‘positive charge’ that attracts hydration to the negatively charged eye’s surface.4,19
  • Mineral oils that target the fatty oil outer layer of the eye.4,19
  • Glycerol to support lubrication and comfort.4,19
  • Spreads fast across the surface of the eye.6,20
  • Ionic technology means increased adherence onto the surface of the eye and therefore, may not need to be reapplied as often as alternative eye drops*3,5,6

Cationorm also contains tyloxapol, poloxamer 188, tris-hydrochloride, tromethamine and water.4,19

THE BENEFITS OF ALOE VERA 

Ocutears Alo+ contains aloe vera for prolonged freshness and long-lasting comfort.2

Aloe vera is a moisturiser and antioxidant shown to have antimicrobial and anti-inflammatory properties which helps to reduce redness and swelling.21-25

Which Ocutears product should I recommend?

  • Choose Hydro+: Busy lifestyle impacted by dry eye symptoms and wants long-lasting relief, which may mean less frequent application of eye drops.1,3,5 Mild-moderate DED.
  • Choose Alo+: Mainly concerned about redness or general irritation. Also, for travellers, those with irritation from sun exposure, air conditioning or a dry environment.2 Mild-moderate DED.
  • Choose Cationorm: Those with regular symptoms that could be exacerbated by the menopause or other conditions.4,11,12 Also suitable for those who have undergone eye surgery and want something to help with the discomfort.4,14 Moderate-severe DED.6,13,14

Compare our eye drops1,2,4,6

  Ocutears® Hydro+ Ocutears® Alo+ Cationorm®
Long-lasting relief
High degree of hydration
Prolonged freshness
Corneal protection
Preservative-free
0.4% cross-linked sodium hyaluronate
Contains aloe vera - a moisturiser and antioxidant
Uses ionic technology
Clinically proven to target oily, watery and mucus layers (Triple Action)
Can be used with contact lenses
Can relieve discomfort after eye surgery
Suitable for those exposed to environmental factors such as, prolonged sunlight, air-conditioned rooms and prolonged screen use

FAQ

Studies show that preservatives in eye drops can make DED symptoms worse over time, negatively affecting the surface of the eye.26,27 Therefore, preservative-free artificial tears are generally recommended for long-term use.27 All Ocutears products – Alo+, Hydro+ and Cationorm – are preservative-free and suitable for everyday use.1,2,4

All Ocutears products – including Hydro+, Alo+ and Cationorm – are preservative-free and contact lens friendly.1,2,4 Preservative-free eye drops are highly recommended for contact lens wearers, as well as those who need to apply eye drops frequently, have known allergies to preservatives or have ocular surface disease.28

This is because most preservatives act as detergents or by oxidative mechanisms and can cause side effects on the eye’s surface and may affect the lens, trabecular meshwork and the retina.28 Over time, preservatives in eye drops can make DED worse.26,27

Download our Pharmacy Leaflet.

For further questions, please fill in the enquiry form and a Santen representative will contact you shortly.

Santen 130+ years expertise in ophthalmology badge

EXPERTS YOU CAN TRUST

The Ocutears range is brought to you by Santen; experts you can trust.

As specialists in ophthalmology, Santen is continually advancing dry eye disease care, with more than 130 years of experience developing innovative products that improve the lives of people living with eye conditions.29,30

Founded in Japan over a century ago, we’re proud to be a world leader in eye care, including in glaucoma, dry eye, vernal keratoconjunctivitis, blepharitis, allergies and eye surgery, and of our mission to better protect the world’s sight.31

Find out more about us at santen.co.uk.

  1. Ocutears® Hydro+ 0.4% instructions for use, 2020
  2. Ocutears® Alo+ 0.4% instructions for use, 2020
  3. NHS University Hospitals Sussex. Sodium Hyaluronate 0.2% Eye Drops: Patient Information 2021
  4. Cationorm® patient information leaflet 2019
  5. Arzneimittel GmbH. Hylo-forte Instructions for Use 2018
  6. Daull, P. et al. J Ocul Pharmacol Ther 2020;36:355–365
  7. Karpecki P. Contact Lens Spectrum; July 2009, Last accessed March 24. Available at: https://clspectrum.com/issues/2009/july/inflammation-in-dry-eye-disease/
  8. Guo LW, Akpek E. Turk J Med Sci. 2020 Nov 3;50(SI-2):1611-1615
  9. Uchino M, Yokoi N, Shimazaki J, Hori Y, Tsubota K, Journal of Clinical Medicine. 2022; 11(2):367
  10. Asbell P, Messmer E, Chan C, Johnson G, Sloesen B, Cook N. BMJ Open Ophthalmol. 2019 Dec 5;4(1):e000315. doi: 10.1136/bmjophth-2019-000315
  11. Cook N, et al. Ophthalmol Ther 2019;8:407–420 
  12. McDonald M, et al. Ocul Surf 2016;14(2):144–167
  13. Robert PY, et al. Eur J Ophthalmol 2016;26:546–555;
  14. Amrane M, et al. J Fr Ophtalmol 2014;37:589–98
  15. Posarelli C et al. J Ocul Pharmacol Ther 2019;35:381–387 
  16. Fallacara A, et al. Molecules 2017;22:2104
  17. Williams DL, Mann Bk. PLoS One 2014;9(6):e99766
  18. Simmons PA et al. Clin Opthalmol 2017;11:1637-1642
  19. Cationorm® Product Support Dossier 
  20. Lyseng-Williamson, K.A. Drugs Ther Perspect 2016;32;317-322
  21. Rahmani AH et al. Pharmacogn Rev 2015;9:120–6
  22. Sánchez M et al. Molecules 2020;25:1324
  23. Woźniak A and Paduch R. Pharm Biol 2012;50:147–54
  24. Fox LT et al. Pharmacogn Mag 2014;10(Suppl 2):S392–403
  25. Hamman JH et al. Molecules 2008;13:1599–1616
  26. Nasser L, et al. Clin Ophthalmol 2018;12:1519-1525
  27. Hynnekleiv L et al. Acta Ophthalmol 2023: doi:10.1111/aos.15675
  28. Messmer, E. Ophthalmologe 109, 1064–1070 (2012). https://doi.org/10.1007/s00347-012-2638-4
  29. Santen Pharmaceutical Co. Ltd. Last accessed February 24. Available at: https://www.santen.eu/our-vision/about-santen/Ophthalmology-is-our-sole-focus
  30. Santen Pharmaceutical Co. Ltd. Last accessed February 24. Available at: https://www.santen.uk/our-vision/about-santen 
  31. Santen Pharmaceutical Co. Ltd. Last accessed February 2024. Available at: https://www.ocutears.co.uk/about-ocuwellness/ 
  32. Versura P, Giannaccare G, Campos EC. Sex-steroid imbalance in females and dry eye. Curr Eye Res. 2015 Feb;40(2):162-75. doi: 10.3109/02713683.2014.966847. Epub 2014 Oct 7. PMID: 25290221.

*Compared to alternative eye drops which use a sodium hyaluronate formula which isn’t cross-linked