INFORMATION FOR HEALTHCARE PROFESSIONALS
This information is intended for a healthcare professional audience only. If you are not a healthcare professional, please visit our consumer site.
*compared to alternative eye drops which use a sodium hyaluronate formula which isn’t cross-linked
97% FEEL FRUSTRATED BY THE IMPACT OF SYMPTOMS†
†in a survey of 751 participants
Dry eye disease (DED) can negatively affect quality of life and lock patients into a cycle of frustration.8
BREAK THE DED FRUSTRATION CYCLE
- DED can be a vicious cycle8
- To break it, restoring the ocular surface and tear film integrity may be important8
- Eye drops are the principal approach8
- But frequent eye drop applications are challenging, particularly for those with poor vision or dexterity9
- How often they need to reapply is considered most important to patients when it comes to using an eye drop (96%‡)10
‡in a survey of 160 people.
WHAT MAKES OCUTEARS DIFFERENT
Ocutears’ ionic (Cationorm) and cross-linked formulas 0.4% sodium hyaluronate (Alo+ and Hydro+) formulas are long lasting and are designed to stay put on the eye where they are needed.1-6 That means potentially fewer applications*, with relief from just one drop a day.1-6 All our products are preservative free and contact lens friendly.1,2,4
*compared to alternative eye drops which use a sodium hyaluronate formula.
-
Ocutears Hydro+
Long lasting hydration and relief from sore, stinging, gritty, tired, heavy or watery eyes caused by dry eye.1
Your customer
Busy and needs an eye drop that they can rely on and can apply less often.* Mild-moderate DED.1,2,6
RRP £14.99**
Ocutears Hydro+ is available to order in the UK
-
Ocutears Alo+
Relieves symptoms of red, irritated and sensitive eyes for prolonged freshness and long-lasting comfort.2 Also contains cross-linked version of 0.4% sodium hyaluronate.2
Your customer
Mainly concerned about redness or general irritation.2 Also for travellers, those with irritation from sun exposure, air conditioning or a dry environment.2 Mild-moderate DED.1,2,6
RRP £14.99**
Ocutears Alo+ is available to order in the UK
-
Cationorm
Unique advanced triple-action dry eye science.6 Acts like the body’s natural tears to provide long-lasting relief.6
Your customer
Those with regular symptoms that could be exacerbated by the menopause or other conditions.4,11,12,32 Also suitable for those who have undergone eye surgery and want something to help with the discomfort.4,13 Moderate-severe DED.6,13,14
RRP £14.99**
Cationorm is available to order in the UK
** Excl. VAT. Based on RRP £14.99. Pricing is at the sole discretion of the retailer. Any reference to pricing is for modelling purposes only.
THE BENEFITS OF CROSS-LINKED
Ocutears Hydro+ and Alo+ contain sodium hyaluronate (0.4%) at a higher concentration than other artificial tears.1,2,6,15 Sodium hyaluronate hydrates, lubricates and acts as a barrier to prevent irritation16:
- Most sodium hyaluronate in eye drops is in a linear form16,17
- Cross-linking involves linking together different chains of sodium hyaluronate with two or more bonds, which:
- Increases viscoelasticity16,17
- Works to keep the eye drops in place1,15,18
- Means they may not need to be reapplied as often (vs alternatives without cross-linked sodium hyaluronate)1,3,15
- Provided long lasting hydration and DED symptom relief1
THE BENEFITS OF IONIC
- Clinically proven, Cationorm is a first-of-a-kind artificial tear which uses ionic technology to mimic the body’s natural tears and provide long-lasting relief:4,6,19
- Cetalkonium chloride (CKC) brings the ionic ‘positive charge’ that attracts hydration to the negatively charged eye’s surface.4,19
- Mineral oils that target the fatty oil outer layer of the eye.4,19
- Glycerol to support lubrication and comfort.4,19
- Spreads fast across the surface of the eye.6,20
- Ionic technology means increased adherence onto the surface of the eye and therefore, may not need to be reapplied as often as alternative eye drops*3,5,6
Cationorm also contains tyloxapol, poloxamer 188, tris-hydrochloride, tromethamine and water.4,19
THE BENEFITS OF ALOE VERA
Ocutears Alo+ contains aloe vera for prolonged freshness and long-lasting comfort.2
Aloe vera is a moisturiser and antioxidant shown to have antimicrobial and anti-inflammatory properties which helps to reduce redness and swelling.21-25
Which Ocutears product should I recommend?
- Choose Hydro+: Busy lifestyle impacted by dry eye symptoms and wants long-lasting relief, which may mean less frequent application of eye drops.1,3,5 Mild-moderate DED.
- Choose Alo+: Mainly concerned about redness or general irritation. Also, for travellers, those with irritation from sun exposure, air conditioning or a dry environment.2 Mild-moderate DED.
- Choose Cationorm: Those with regular symptoms that could be exacerbated by the menopause or other conditions.4,11,12 Also suitable for those who have undergone eye surgery and want something to help with the discomfort.4,14 Moderate-severe DED.6,13,14
Product comparison1,2,4,6
Ocutears® Hydro+
|
Ocutears® Alo+
|
Cationorm® |
|
|---|---|---|---|
| Long-lasting relief | |||
| High degree of hydration | |||
| Prolonged freshness | |||
| Corneal protection | |||
| Preservative-free | |||
| 0.4% cross-linked sodium hyaluronate | |||
| Contains aloe vera - a moisturiser and antioxidant | |||
| Uses ionic technology | |||
| Clinically proven to target oily, watery and mucus layers (Triple Action) | |||
| Can be used with contact lenses | |||
| Can relieve discomfort after eye surgery | |||
| Suitable for those exposed to environmental factors such as, prolonged sunlight, air-conditioned rooms and prolonged screen use |
FAQ
Studies show that preservatives in eye drops can make DED symptoms worse over time, negatively affecting the surface of the eye.26,27 Therefore, preservative-free artificial tears are generally recommended for long-term use.27 All Ocutears products – Alo+, Hydro+ and Cationorm – are preservative-free and suitable for everyday use.1,2,4
All Ocutears products – including Hydro+, Alo+ and Cationorm – are preservative-free and contact lens friendly.1,2,4 Preservative-free eye drops are highly recommended for contact lens wearers, as well as those who need to apply eye drops frequently, have known allergies to preservatives or have ocular surface disease.28
This is because most preservatives act as detergents or by oxidative mechanisms and can cause side effects on the eye’s surface and may affect the lens, trabecular meshwork and the retina.28 Over time, preservatives in eye drops can make DED worse.26,27
Download our Pharmacy Leaflet.
For further questions, please fill in the enquiry form and a Santen representative will contact you shortly.
EXPERTS YOU CAN TRUST
The Ocutears range is brought to you by Santen; experts you can trust.
As specialists in ophthalmology, Santen is continually advancing dry eye disease care, with more than 130 years of experience developing innovative products that improve the lives of people living with eye conditions.29,30
Founded in Japan over a century ago, we’re proud to be a world leader in eye care, including in glaucoma, dry eye, vernal keratoconjunctivitis, blepharitis, allergies and eye surgery, and of our mission to better protect the world’s sight.31
Find out more about us at santen.co.uk.
- Ocutears® Hydro+ 0.4% instructions for use, 2020
- Ocutears® Alo+ 0.4% instructions for use, 2020
- NHS University Hospitals Sussex. Sodium Hyaluronate 0.2% Eye Drops: Patient Information 2021
- Cationorm® patient information leaflet 2019
- Arzneimittel GmbH. Hylo-forte Instructions for Use 2018
- Daull, P. et al. J Ocul Pharmacol Ther 2020;36:355–365
- Karpecki P. Contact Lens Spectrum; July 2009, Last accessed March 24. Available at: https://clspectrum.com/issues/2009/july/inflammation-in-dry-eye-disease/
- Guo LW, Akpek E. Turk J Med Sci. 2020 Nov 3;50(SI-2):1611-1615
- Uchino M, Yokoi N, Shimazaki J, Hori Y, Tsubota K, Journal of Clinical Medicine. 2022; 11(2):367
- Asbell P, Messmer E, Chan C, Johnson G, Sloesen B, Cook N. BMJ Open Ophthalmol. 2019 Dec 5;4(1):e000315. doi: 10.1136/bmjophth-2019-000315
- Cook N, et al. Ophthalmol Ther 2019;8:407–420
- McDonald M, et al. Ocul Surf 2016;14(2):144–167
- Robert PY, et al. Eur J Ophthalmol 2016;26:546–555;
- Amrane M, et al. J Fr Ophtalmol 2014;37:589–98
- Posarelli C et al. J Ocul Pharmacol Ther 2019;35:381–387
- Fallacara A, et al. Molecules 2017;22:2104
- Williams DL, Mann Bk. PLoS One 2014;9(6):e99766
- Simmons PA et al. Clin Opthalmol 2017;11:1637-1642
- Cationorm® Product Support Dossier
- Lyseng-Williamson, K.A. Drugs Ther Perspect 2016;32;317-322
- Rahmani AH et al. Pharmacogn Rev 2015;9:120–6
- Sánchez M et al. Molecules 2020;25:1324
- Woźniak A and Paduch R. Pharm Biol 2012;50:147–54
- Fox LT et al. Pharmacogn Mag 2014;10(Suppl 2):S392–403
- Hamman JH et al. Molecules 2008;13:1599–1616
- Nasser L, et al. Clin Ophthalmol 2018;12:1519-1525
- Hynnekleiv L et al. Acta Ophthalmol 2023: doi:10.1111/aos.15675
- Messmer, E. Ophthalmologe 109, 1064–1070 (2012). https://doi.org/10.1007/s00347-012-2638-4
- Santen Pharmaceutical Co. Ltd. Last accessed February 24. Available at: https://www.santen.eu/our-vision/about-santen/Ophthalmology-is-our-sole-focus
- Santen Pharmaceutical Co. Ltd. Last accessed February 24. Available at: https://www.santen.uk/our-vision/about-santen
- Santen Pharmaceutical Co. Ltd. Last accessed February 2024. Available at: https://www.ocutears.co.uk/about-ocuwellness/
- Versura P, Giannaccare G, Campos EC. Sex-steroid imbalance in females and dry eye. Curr Eye Res. 2015 Feb;40(2):162-75. doi: 10.3109/02713683.2014.966847. Epub 2014 Oct 7. PMID: 25290221.
*Compared to alternative eye drops which use a sodium hyaluronate formula which isn’t cross-linked